Alfred E. Mirsky Professor and Head of the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology
Bruce McEwen, Ph.D, is an Alfred E. Mirsky Professor and Head of the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at the Rockefeller University in New York. Dr. McEwen received his B.A. in chemistry from Oberlin College in 1959 and his Ph.D. in cell biology from The Rockefeller University in 1964 under the mentorship of Drs. Vincent Allfrey and Alfred E. Mirsky. He was a United States Public Health Service Postdoctoral Fellow at the Institute of Neurobiology in Göteborg in Sweden. Dr. McEwen returned to the Rockefeller University in 1966.
Dr. McEwen's laboratory has carried out groundbreaking research, discovering adrenal steroid receptors and, later, estrogen receptors in the hippocampus, a brain region that mediates memory and mood regulation. These discoveries, now expanded to other brain regions such as amygdala, prefrontal cortex, and nucleus accumbens, showed that circulating stress and sex hormones do more in the brain than just provide feedback to regulate neuroendocrine function, but rather influence cognitive and emotional processes throughout the life course, with major implications for anxiety and depressive disorders. Indeed, he has gone on to show that acute and chronic stress causes remodeling of synapses and dendrites in man anxiety- and depression-related brain regions and that there is neurogenesis throughout life in the dentate gyrus of the hippocampal formation, which is increased by anti-depressant treatments.
Dr. McEwen is author of over 1000 publications. He is past president of the Society for Neuroscience and member of the National Academy of Sciences and the National Academy of Medicine. Dr. McEwen has received many awards, including the Dale Medal of the British Endocrine Society, the Karl Spencer Lashley Award, American Philosophical Society, the Scolnick Prize in Neuroscience from MIT, the Ipsen Foundation Prize in Neuronal Plasticity, the Society for Biological Psychiatry Gold Medal and the Thomas W. Salmon Award from the New York Academy of Medicine.
Grants and Funding: We proudly support the research and programs of 501(c)(3) non-profit organizations and institutions such as: the Anxiety Disorders program of the Jane & Terry Semel Institute for Neuroscience & Human Behavior at the University of California, Los Angeles; the Pacific Institute of Medical Research; the International Foundation for Research and Education on Depression (iFred); and SchoolsForHope.org, an iFred educational project. Working with these partners enables Anxiety.org to extend its commitment to its mission. All the donations received, as well as 100% of Anxiety.org revenue in 2019, will be contributed to build, develop, and further the understanding, investigation, discovery, and treatment of the full spectrum of anxiety and related disorders.