In a society conscious of aging, myriad advertisements promote products purporting to counteract the effects of time, leading individuals on a quest to preserve their aesthetics and health. Nevertheless, the efficacy of these anti-aging solutions varies widely.
The market offers a variety of products that cater to both the physical and visual aspects of aging. One notable anti aging supplement that has gained attention is Nicotinamide mononucleotide (NMN). In this article we will explore some of the products available on the market and present the best NMN supplement.
After introducing the topic and describing our top three NMN supplements, we have carefully compiled a comprehensive list of the most important supplements for 2023 and thoroughly researched all the relevant data. Reading our article will ensure that you have all the essential details about an NMN supplement.
Best Product: GenF20 Liposomal NMN Supplement
- High quality ingredients
- More vitality & energy
- Highest bioavailability
- Price: 69,95 USD
GenF20 Liposomal NMN+ is a company that produces high quality NMN capsules. These capsules are carefully made without any gluten, GMOs, additives, preservatives, soy or dairy. The company strictly follows GMP guidelines. Meets U.S. Criteria. To ensure their quality and safety the capsules undergo third party laboratory verifications and are overseen by the FDA.
A principal advantage of the Liposomal NMN Supplement is their rich antioxidant composition, fostering optimal NAD+ levels and decelerating the aging process. Beyond product excellence, Liposomal NMN+ extends rewards and fidelity schemes, allowing patrons to accrue points redeemable through referrals or sustained subscriptions.
In terms of pricing GenF20 Liposomal NMN is quite competitive with its products ranging from $58.95 to $69.95. A bottle containing 500mg is priced at $1 per unit while the 300mg costs $2, per unit. As a result we confidently recommend this product as our choice!
Manufacturer: GenF20 Liposomal NMN
Pros: Validated by impartial labs, refund assurance, markedly efficacious, and premium constituents.
Second Place: PartiQlar
- More energy, power and health
- Improves endurance and strength
- Good value for money
- Price: 71,99 USD
Welcome to the realm of Partiqlars Pure NMN Supplement, where boundless possibilities await you. Prepare yourself for a life changing journey filled with health benefits and unique encounters. PartiQlar NMN is not just a product; it embodies the highest standards of excellence and serves as a catalyst, for positive transformation.
Transition into a revitalized epoch of health and vigor, as PartiQlar’s Pure NMN surpasses anticipated benchmarks. This premier product is diligently formulated to amplify your vitality, foster cellular rejuvenation, and enhance your comprehensive well-being. With its distinctive composition, PartiQlar NMN stands preeminent in the health supplement sector, epitomizing a synthesis of effectiveness and novelty.
Experience the wonders of PartiQlars NMN Supplement and unlock a revitalizing enthusiasm that permeates every aspect of your life. Embrace the boost in your energy. The improvement in your mental clarity. Bid farewell to fatigue and embrace a world brimming with renewed vitality increased productivity and passion. PartiQlar Pure NMN goes beyond being a product; it serves as a gateway, to an enhanced version of yourself.
Pros: Decelerates the aging process, enhances energy vigor, and augments endurance & fortitude.
Third Place: RENUE by SCIENCE - LIPO NMN Supplement
The latest development in the world of supplements is Renue Lipo NMN Supplement, touted as the pioneering liposomal variant of NMN. Essentially, this indicates that the NMN is enveloped within a lipid-based vesicle, potentially optimizing NMN uptake. Presently, concrete data is lacking to establish if the liposomal NMN indeed surpasses its traditional powdered NMN in absorption. Nevertheless, the consensus in the industry suggests that certain supplements benefit from liposomal encapsulation in terms of absorption.
Renue champions a premium supplement composition, incorporating rice flour and devoid of artificial additives. At a price point of USD 84.95, it occupies a premium segment, but many consider its cost to be justifiable.
Pros: Shrouded in a liposomal NMN shell, free from extraneous fillers or additives, validated through impartial third-party assessments, each dose delivers 500mg of NMN, equating to two capsules.
Fourth Place: Wow!Health Ageless
- More power & energy
- Improved neural function in the brain
- Monay-back guarantee
- Price: 64,99 USD
Wow! The company Wow!Health manufactures NMN supplements in the United States following the GMP and HACCP protocols, in their production facilities. These high quality capsules of nicotinamide mononucleotide are sourced from plants. Guarantee a purity level of 100%.
Leveraging cutting-edge technology amplifies the supplement’s bioavailability, ensuring effective cellular and tissue penetration of the stipulated NMN quantity. Beyond pure NMN, each Wow!Health capsule is enriched with pivotal trace elements and minerals.
To achieve effectiveness Wow!Health recommends taking two NMN Supplement capsules each day; one before breakfast in the morning and another in the afternoon. They offer shipping, within the United States but they have not yet introduced a monthly subscription service. However both new and returning customers can enjoy price reductions.
Pros: Refund assurance, derived from plants, markedly efficacious, and vegan-aligned.
Fifth Place: Wonderfeel Youngr NMN Supplement
The Youngr NMN Supplement, brought to you by Wonderfeel aims to promote the process of aging. It contains antioxidants, sirtuin enhancers and a powerful dose of 900mg of NMN. Users have reported benefits such, as increased energy levels, enhanced memory, improved skin elasticity and better quality sleep. To maximize the absorption of resveratrol and reap its aging effects it is recommended to take the supplement with breakfast meals that include healthy fats.
Currently, Wonderfeel extends a promotional price for both subscription models and singular purchases, allowing patrons to avail a $15 discount and secure this pricing. The Wonderfeel online platform showcases customer testimonials for deeper insights into the product.
It is extremely important to emphasize that although NMN supplements have their advantages they should not be seen as a substitute for treatments. Regular consultations with a healthcare provider are still crucial, for maintaining health.
Pros: The item showcases a proprietary blend developed by a Harvard MD, delivering a robust 900mg of NMN per intake. Consumers have lauded it with outstanding feedback, noting enhancements in energy, memory, and skin suppleness.
Cons: The statement is presented in English as requested.
Sixth Place: OMRE NMN
- More energy, power and agility
- Good value for money
- Third-party tested
- Price: 49,97 USD
The Omre NMN Supplement undergoes testing for purity and safety during every stage of production, which is conducted in independent laboratories. The supplement is sold at a rate of $4.05, per gram. Additionally a bottle containing 60 capsules, each with a dosage of 300mg has a price of $44.80 but is currently being offered on Amazon at a discounted price of $42.57.
While Omre extends various promotions and perks, bulk acquisitions might not always yield financial benefits. Purchases surpassing $75 are eligible for complimentary shipping. Conversely, orders below $75 bear a shipment charge of $4.99 for standard delivery, or $12 for FedEx’s two-day delivery service.
Omre truly prioritize the quality and safety of the products. They take measures to evaluate them thoroughly. Moreover they offer a range of pricing and delivery options to cater to the diverse needs and preferences of there customers.
Pros: The supplement prides itself on superior absorption and eschews chemical solvents or synthetic additives. Furthermore, it offers a 30-day refund assurance.
Cons: Regrettably, this item is not available for online procurement, and details on third-party evaluations and their outcomes remain undisclosed.
Seventh Place: Quicksilver NAD+ NMN Supplement
- More power & energy
- Very positive customer reviews
- Tested by third-party laboratories
- Price: 112,00 USD
The QuickSilver NMN Supplement is regularly tested by labs to guarantee its purity and consistency. This supplement has a combination that includes platinum and advanced liposomal technology mimicking how NMN is distributed in the body. This ensures that important elements reach targeted areas, for effectiveness. Its liquid form also allows for absorption and potency.
Optimal for individuals desiring prompt outcomes, the supplement is enriched with vitamin B12, crucial for blood and nerve cell maintenance, and riboflavin, which offers anti-inflammatory properties, aids in slowing the aging process, and delivers antioxidant advantages.
Pros: The item is devoid of GMOs and aligns with vegan standards. Undergoing third-party verification, it employs liposome innovation. It has garnered exemplary feedback from consumers.
Cons: Upon purchase, the products necessitate prompt refrigeration and uphold a non-returnable policy for displeasing or impaired goods. Some consumers deem the pricing steep.
Eigth Place: Double Wood
- Fast & positive effects
- Medically tested
- Natural ingredients
- Price: 79,99 USD
This NMN Supplement is made in the USA using high quality ingredients. It has undergone testing by independent laboratories to ensure its purity and effectiveness. While the usual daily dose of NMN ranges from 250 mg to 1500 mg this brand only offers doses, between 250 mg and 500 mg.
To attain a dosage of 250 mg, consumers are advised to ingest one 125 mg capsule in the morning and another in the afternoon. For a heightened dosage, an initial 125 mg capsule can be paired with subsequent capsules over the next one to three hours. New clientele can acquire a 60-count bottle of 125 mg at $48.95, whereas recurring and subscribing customers are offered a discounted rate of $43.08.
Manufacturer: Double Wood
Pros: Free from GMOs and gluten, validated by independent laboratories, and overseen by the FDA.
Cons: Limited in availability, not economically accessible.
What is NMN?
Nicotinamide Mononucleotide (NMN) is a compound believed to increase the levels of Nicotinamide Adenine Dinucleotide (NAD) in the body. This increase, in NAD levels may provide both external anti aging benefits.
NAD is instrumental in bodily functions, overseeing energy metabolism, facilitating DNA repair, and managing stress responses.
Ongoing research on humans suggests that a good NMN Supplement may have an impact on the aging process. This impact goes beyond external appearance and also affects internal factors such as the health of blood vessels, efficient circulation, muscle vitality and overall vulnerability, to illnesses.
Understanding NMN & NAD+ (A Brief Overview)
Nicotinamide mononucleotide (NMN) plays a role in the production of NAD, which is an essential energy molecule. Without NAD cellular activity would come to a halt within moments. It is crucial for every cell and governs over 500 enzymes in the body. Some important functions of NAD include;
- Activating sirtuins, which’re proteins that help mitigate the effects of aging.
- Enhancing energy production through the Krebs cycle.
- Repairing damaged DNA through PARP1.
- Synthesizing hormones.
- Supporting muscle development.
- Promoting recovery.
Sirtuins have gained scientific interest for their ability to strengthen our bodys natural defenses. However their effectiveness relies heavily on maintaining levels of NAD.
As we age our levels of NAD naturally decline. By the age of 50 most individuals have half the amount of NAD compared to their twenties. Decreased levels of NAD can accelerate the aging process. Limiting your overall health span highlights the importance of supplementing with a good NMN supplement.
NMN is a created nucleotide that serves as an immediate precursor to NAD and is crucial for smooth cellular functioning. For a detailed exploration on this topic you may want to listen to David Sinclairs discussion, on the Joe Rogan Experience podcast.
Nicotinamide Mononucleotide (NMN) Benefits
Nicotinamide Mononucleotide (NMN) has garnered significant attention in the realm of health and longevity. Unlike direct NAD+ supplementation which may have localized effects, NMN serves as a systemic NAD booster, revitalizing aging tissues throughout the body. Prominent figures in the health sector, such as David Sinclair, Dr. Axe, Dr. Berg, Dr. Hyman, Dr. Rhonda Patrick, and Dr. Peter Attia, often shed light on its potential benefits.
NMN’s benefits stem not just from the molecule itself but also from its capacity to elevate NAD+ levels. The scientific community continues to uncover more of its health implications every day. Some of the identified benefits of a NMN Supplement include:
- Rejuvenation in Animal Models: NMN has been observed to rejuvenate mice.
- Brain Health: NMN shows promise in bolstering cognition among Alzheimer’s patients, defending against neurodegeneration, and enhancing memory.
- NAD+ Boosting: NMN can drastically increase levels of NAD+ in the body.
- Immune Function: It can improve overall immune response, bolster resistance to microbes, and offset immunodeficiency.
- Energizing Cells: It promotes energy metabolism at the cellular level.
- Regulating Blood Sugar: It can enhance insulin sensitivity, providing defense against diabetes, fatty liver disease, and obesity.
- Overall Wellbeing: Regular NMN supplementation can lead to a greater sense of wellbeing.
- Body Composition: It may help reduce fat mass and increase lean muscle mass.
- Circulatory Health: NMN promotes better blood flow and can havecardioprotective effects.
- Aging and Performance: From emulating the benefits of caloric restriction and protecting the heart to enhancing overall performance and mobility in older individuals, NMN offers various anti-aging benefits.
- Potential in Pandemics: Preliminary data suggests it may be beneficial in treating conditions like COVID.
- Mitochondrial Vitality: It promotes the health of mitochondria, the cell’s powerhouses.
- DNA Integrity: NMN aids in DNA repair, ensuring genetic stability.
- Reproductive Health: NMN might help restore fertility.
NMN Absorption Methods: An Essential Guide for Consumers
The efficacy of NMN is greatly determined by its absorption rate. A crucial aspect to consider when purchasing a NMN supplement is the delivery mechanism, as it can shape the product’s overall impact, strength, potential side effects, and overall value.
|Pure NMN||Sublingual NMN||Intranasal NMN||Liposomal NMN|
|Duration||Short||Medium||Short||Up to 24 hours|
|Feature||Convenience||Noticeable energy boost||Neuroprotective, clears brain fog||Extended release, highest bioavailability|
|Price||Least expensive||Moderate||Moderate||Most expensive|
Caption: NMN Comparison Table – Oral, Sublingual, Liposomal, and Intranasal
Standard NMN Powder
Traditional NMN powders typically offer a more economical choice and have been extensively studied. However, they tend to exhibit the least efficient absorption. The gastric acid can degrade unshielded NMN and NR into nicotinamide (NAM) before reaching crucial tissues. To offset this reduced absorption, higher dosages of NAD enhancers might be administered. However, this can lead to an elevated NAM level, potentially impairing sirtuins, which are vital for cellular health and longevity.
When you take NMN sublingually you allow it to dissolve under your tongue. Some brands have developed techniques to bypass liver processing, which helps the NMN enter the bloodstream more quickly and potentially improves absorption. Usually this method is more expensive compared to using powders. People who have tried NMN often report feeling an immediate increase, in energy.
Yet, there’s scant data on how much the bioavailability truly improves compared to oral intake. For those seeking tangible results from their supplements, the pronounced impact of a sublingual NMN Supplement might offer confidence.
Intranasal NMN Delivery
A intranasal NMN supplement is a newer method of introducing the compound to the body. Its distinctive advantage lies in its capacity to sidestep the blood-brain barrier, thereby elevating NAD levels directly within the brain.
Compared to taking medicine using the intranasal method requires smaller doses has fewer side effects and has a stronger impact on the brain. Initial research suggests that it may have the potential to restore energy levels after experiencing traumatic brain injuries. However due, to its supply intranasal NMN tends to be more expensive.
The use of technology has brought about a significant change in the delivery of certain supplements in the body. Specifically liposomal NMN supplements offer improved absorption rates and less degradation in the system compared to non liposomal versions. This results in a release of NMN leading to increased NAD levels, throughout the entire day.
At their core, liposomes are tiny lipid-based vesicles, mirroring the structure of human cell membranes. These vesicles shield their contents from the harsh environment of the stomach, leading to superior delivery and utilization in the body. Liposomal methods, though developed back in the 1960s, have gained renewed interest as potential game-changers in the dietary supplement realm.
The discourse on liposomal NMN, however, is still a subject of debate among experts. Studies, like those conducted by Dr. Christopher Shade, indicate that liposomal encapsulation can potentially amplify the absorption of supplements by 3 to 10 times. This implies a higher potency at reduced doses, offering consumers better value for their money. However, due to the intricate production methods, liposomal NMN tends to command a premium price in the market.
NMN Supplement Dosage Guidelines
Finding the dosage of NMN is crucial to maximize its potential benefits. Although NMN supplements come with recommended dosages on their labels it’s important to note that there isn’t an amount that suits everyone. To achieve results it is generally advised to consume NMN in smaller portions spread throughout the day rather than taking one large dose.
There are various forms of NMN available, including NMN powder, capsules, sublingual powder, and intranasal NMN, the latter being a nasal spray. Some proponents argue that intranasal NMN and sublingual powder are superior in effectiveness due to their unique delivery methods.
The recommended amount of NMN can differ from person to person so it’s important to experiment and find the dosage for yourself. If you’re new to a NMN Supplement it’s an idea to start with a small amount and then gradually adjust based on how you feel and the effects you desire. However make sure to follow the instructions, on the label of your chosen supplement since potency may vary between products.
Lastly, embarking on any new supplementation regime should always involve a discussion with a healthcare professional, especially if you’re on medications or other supplements, to avoid potential interactions and ensure safety.
Selecting the Ideal NMN Supplements
In the quest for the most suitable nicotinamide mononucleotide supplement, it's vital to opt for a distinguished product that not only offers the requisite NMN dosage but also embodies specific attributes.
Essential aspects to ponder upon are:
Essential aspects to ponder upon are:
- Independent Verification: Opt for a supplement that's subjected to impartial third-party analysis, ensuring adherence to robust manufacturing standards and the exclusion of contaminants like heavy metals.
- Purity of the supplement: Unwavering dedication to the purity of the supplement by the company
- Stellar Customer Support: Prioritize brands that uphold customer contentment and affordability. This can be gauged via customer testimonials that shed light on genuine user encounters.
- Cost-Effectiveness: Target a supplement that aligns with your financial means, bearing in mind that consistency is key to effectiveness, necessitating regular acquisitions.
Heeding these guidelines will empower you to discerningly select an NMN supplement aligning with your prerequisites.
How to Naturally Elevate NAD Levels
NAD (Nicotinamide Adenine Dinucleotide) levels in the body can be enhanced through two main approaches:
- Supplementation: Utilizing specifically designed boosters.
- Optimization: Enhancing the inherent processes, especially by activating the salvage pathway. This approach tends to offer more sustainable and lasting benefits.
For those interested in natural methods to boost NAD without resorting to a NMN supplement, consider the following:
- Raw Honey: This natural sweetener has properties that can help raise NAD levels.
- Fermented Foods: Consuming fermented foods can aid in NAD production. Examples include yogurt, kefir, and sauerkraut.
- Sauna Sessions: Regular sessions in a sauna can potentially upregulate the production of NAD.
- Pau D’Arco Tea: This herbal tea, derived from the bark of several species of trees, is believed to have properties that can enhance NAD levels.
- Fasting: Periodic fasting or intermittent fasting can stimulate processes in the body that boost NAD.
To further support NAD levels, you can also consume foods that, while containing only trace amounts of NMN, can contribute to better NAD production:
- Broccoli: This green vegetable is not only nutritious but can also support NAD levels.
- Cucumber: A cool and refreshing veggie that may help with NAD production.
- Kale: A superfood that’s beneficial in many ways, including potentially boosting NAD.
- Avocado: Rich in healthy fats and can contribute to NAD levels.
- Tomatoes: A versatile food that might support NAD production.
- Edamame: Young soybeans that can be a tasty and supportive snack.
By weaving these practices and foods into your daily habits, you can work towards naturally elevating your NAD levels without an exclusive dependence on NMN supplements.
Does the fat loss from using NMN supplements have any effect on the skin?
Losing fat can definitely have a positive effect on the appearance of your skin. For example, unclean skin and being overweight are often linked. Losing fat can also help reduce cellulite and make your skin look smoother. A good NMN Supplement is also known to have a positive effect on skin elasticity, which improves the appearance of the skin.
Will I be able to reach a higher age by taking this supplement?
Taking an NMN supplement alone is unlikely to guarantee that you will live longer. However, taking it will have a positive effect on the symptoms of ageing, which may make you feel a little younger than you actually are.
Frequently asked questions
Is NMN safe?
Animal studies have consistently shown NMN to be safe. Preliminary human studies also indicate a strong safety profile, with subsequent studies echoing these findings. It’s essential, however, to source a NMN supplement from trustworthy, high-quality providers.
NMN vs. NR: Which is better?
NMN has been found to be more stable than NR, and this stability might confer additional health advantages. The body must convert NR to NMN for use. If the NRK enzyme, responsible for this conversion, isn’t efficient, NR might not effectively increase NAD levels. Hence, many researchers in the field of longevity favor NMN over NR.
Are there any side effects of NMN?
Within the recommended dosages, there haven’t been consistent reports of side effects from NMN supplementation. However, another compound, nicotinamide riboside (NR), might impede athletic performance, suggesting athletes might prefer NMN.
How do I know if an NMN supplement is working?
If you want to assess the effectiveness of your NMN supplement you might want to consider getting a NAD test or evaluating your “biological age” before starting the supplement and again after six months. You can find in depth information about this process, in the InsideTracker review.
What is the best dose of NMN?
According to research the recommended daily dosage of nicotinamide mononucleotide varies between 100 mg and 500 mg depending on the form. While some experts propose dosages of up to 1,000 mg, per day it’s important to consider that the likelihood of experiencing side effects may rise with increased doses.
Why take NMN instead of NAD?
While it may be tempting to supplement with NAD the body doesn’t effectively utilize regular NAD powder due to its large size and quick breakdown. However there are methods of delivering NAD, such, as liposomal and intranasal supplementation, which overcome these challenges and have shown greater effectiveness.
Should I take trimethylglycine (TMG) with NMN?
It is frequently recommended to combine a NMN supplement with an amino acid called betaine (also known as TMG) to support the bodys natural methylation processes. This combination can help reduce side effects particularly for individuals who take oral NMN powder for long durations. In the case of using sublingual NMN TMG may be less necessary.
Will MIB-626 replace NMN?
MIB-626, developed by David Sinclair’s MetroBiotech, is a newer NAD booster under investigation for various health benefits. As it’s still in the early stages, it will have patent protection and could generate significant revenue for Metro. However, the research base for MIB-626 is currently sparse compared to the extensive studies on NMN.
Top NMN Supplements to Boost Your NAD Levels
NAD is a crucial molecule for our cellular functions and overall well-being. When we have suboptimal levels of NAD, our performance and vitality may be compromised.
Numerous known scientists specializing in anti aging and longevity strongly support NMN as the preferred supplement for boosting NAD levels. This endorsement is supported by a multitude of accounts, from individuals who have reported increased energy and overall well being after regularly taking an NMN supplement.
For those embarking on their journey to boost NAD levels I suggest starting with precursors. However it is important to consider that certain genetic factors or lifestyle choices may necessitate the use of potent supplements. Specifically, if you possess genes:
To ascertain your real-time NAD levels, you can opt for an intracellular NAD test and follow it up with another test 3-6 months post-supplementation. Such testing can ensure you’re consuming genuine NMN and can aid in decision-making on whether the investment in a NMN supplement is justified for you.
Unfortunately the increasing popularity of NAD boosters has resulted in a flood of low quality products flooding the market. There is a possibility that some of these products may not even contain NMN and others could be contaminated. To prevent wasting money and potentially putting your health at risk it is crucial to obtain your supplements from well known brands.
If you have any insights, questions or personal experiences about NMN Supplements, I’d love to hear them. Feel free to share your thoughts in the comments below!