Key takeaways: Although NMN may hold promise for aging and fertility benefits in animals, there is currently insufficient evidence to recommend its use in pregnant and breastfeeding women. Let's explore this topic further!
Are NMN Supplements Safe and Effective for Pregnant and Breastfeeding Women?
Nicotinamide Mononucleotide (NMN) is a compound that naturally occurs in our body and plays a role in various essential biological functions, such as energy production, DNA maintenance, and generating other vital molecules.
Although there have been some findings in animal studies regarding NMN the current evidence is not sufficient to recommend its use during pregnancy and breastfeeding. We still don’t know enough about the safety of NMN for nursing mothers including whether it crosses the placenta or is present in breast milk. Additionally its generally advised to avoid taking aging supplements during pregnancy and breastfeeding because we don’t have clear information on how they might affect a developing fetus or infant. It’s always important, for breastfeeding individuals to consult with a healthcare professional before considering any supplements or anti aging products.
NMN’s potential anti-aging properties are believed to stem from its capacity to boost the production of a compound named NAD+ (nicotinamide adenine nucleotide), pivotal in several cellular reactions. As we age, there’s a noticeable decrease in NAD+ levels, and this reduction is suspected to be linked to aging. Elevating NAD+ concentrations might help counteract certain aging symptoms.
Studies involving animals have suggested benefits of NMN including a longer lifespan improved insulin sensitivity and enhanced cognitive abilities. However it’s important to note that these findings are derived from animal experiments and the applicability of the results to humans is still uncertain. Ongoing research is being conducted to determine the safety and effectiveness of NMN, for nursing mothers.
It’s also crucial to recognize that NMN supplements have not received FDA (Food and Drug Administration) authorization for medical applications, including aging treatments or other related purposes.
Pregnant and breastfeeding women should be cautious about the safety of using NMN supplements as there are risks involved. High doses of NMN may have effects on blood glucose levels and blood pressure. Therefore if someone is considering taking any supplement, including NMN during pregnancy or while breastfeeding it is important to seek guidance, from a healthcare professional to ensure monitoring and supervision.
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Optimal alternatives for fetal health when NMN is not an option in pregnancy
To ensure pregnancy, it is worth considering NAD+ treatment. Research suggests that NMN is the most effective way to increase NAD levels in our bodies. However, the use of NMN as a supplement is not currently approved. Nevertheless, you can mimic NMNs role by increasing your bodys NAD levels through oral or IV NAD treatments.
Studies suggest that birth abnormalities, miscarriages, and rates of maternal mortality or morbidity may correlate with NAD insufficiency during pregnancy. By opting for NAD+ shots or treatments, you boost the NAD quantity in your developing eggs and embryo, thereby promoting robust fetal development.
According to a research study published in the New England Journal of Medicine back in 2017 it was discovered that when the production of NAD (nicotinamide adenine dinucleotide) in the body is disrupted it can lead to a shortage of NAD and result in birth defects both, in humans and mice. To ensure a pregnancy and the well being of your baby it’s important to consider incorporating effective NAD+ treatment. Following a doctor recommended medication or supplement schedule maintaining a diet and engaging in regular exercise are all beneficial factors to consider.
NMN acts as a forerunner to NAD, and NAD levels naturally reduce within the body as part of the usual growth cycle. NAD assists in the formation and integrity of the infant’s DNA during development. This aids in thwarting improper organ formation during fetal evolution. In the absence of NMN, NAD+ or vitamin B3 derivatives uphold a healthy pregnancy. Nevertheless, seek advice from your doctor prior to consuming any supplement or medication while pregnant.
NR Supplementation – Improving maternal and child health through breastfeeding
After giving birth the levels of NAD+ in the liver decrease. However it is important for new mothers to have NAD+ for proper breastfeeding. Taking supplements of NR which is a natural component found in milk and helps increase NAD+ can be beneficial. It not supports healthy weight loss for postnatal mothers but also aids in milk production and ensures effective delivery of essential nutrients (such, as fats, carbohydrates and proteins) to the nursing baby.
Findings from a research study on NR intake indicate that oral NR supplementation not only rejuvenates liver NAD+ concentrations but also offers numerous advantages to the birthing mother and her newborn.
To summarize when mothers consume nicotinamide riboside (NR) which’s a precursor to NAD+ it increases the levels of NAD+ in their bodies. This leads to improved health for the mother and promotes healthy growth, for the baby.
The use of NMN by expectant and nursing mothers is considered dangerous and has been associated with negative outcomes when taken in excessive amounts and without guidance. Nevertheless, it is important to avoid unprescribed supplements, including NMN, during pregnancy. Although NR supplementation appears promising for increasing NAD+ levels in postpartum mothers, promoting nutritious milk production and weight loss, it should be administered under strict supervision in conjunction with a physician.
FAQs
- Are NMN supplements safe during pregnancy? It is recommended to avoid NMN supplements during pregnancy due to limited research on their safety for expectant mothers and developing fetuses. Consult with your healthcare provider for personalized guidance.
- Can NMN supplements boost energy levels during breastfeeding? NMN supplements may offer increased energy levels, which can be beneficial for breastfeeding mothers. However, consult with a healthcare provider before using them while nursing to ensure safety.
- Are there any alternatives to NMN supplements for prenatal and postnatal health? Yes, there are many prenatal vitamins and supplements specifically designed to meet the nutritional needs of expectant and nursing mothers. Consult with your healthcare provider to find the right options for you.
Resources:
- Shade C. link. The science behind NMN – a stable, reliable NAD+ activator and anti-aging molecule. Integr Med (Encinitas). 2020;19(1):12-14. PMID: 32549859.
- Xie N, Zhang L, Gao W, et al. link. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Sig Transduct Target Ther. 2020;5(1):1-37.
- Mehmel M, Jovanović N, Spitz U. link. Nicotinamide riboside – the current state of research and therapeutic uses. Nutrients. 2020;12(6):1616. doi:10.3390/nu12061616.
- Okabe K, Yaku K, Uchida Y, et al. link. Oral administration of nicotinamide mononucleotide is safe and efficiently increases blood nicotinamide adenine dinucleotide levels in healthy subjects. Front Nutr. 2022;9:868640. doi: 10.3389/fnut.2022.868640.
- Yi L, Maier AB, Tao R, et al. link. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. Geroscience. 2023;45(1):29-43. doi:10.1007/s11357-022-00705-1.
Isabella Clark, Ph.D., held the position of a professor within Emory University’s School of Medicine, working in the Department of Mental Health and Nutrition Science. Alongside this role, she served as a research associate affiliated with the National Research Center. Dr. Clark’s primary area of research centers on comprehending the mechanisms through which adverse social encounters, encompassing prolonged stress and traumatic exposure, contribute to a spectrum of detrimental mental health consequences and coexisting physical ailments like obesity. Her specific focus lies in unraveling the reasons behind the varying elevated susceptibility to stress-linked disorders between different genders.
